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	Provedor de dados ArchiMer (2) Autor Schmitt, Paulina (2) Bachere, Evelyne (1) De Lorgeril, Julien (1) Destoumieux-garzon, Delphine (1) Destoumieux-garzón, Delphine (1) Duperthuy, Marylise (1) Gueguen, Yannick (1) Vanhove, Audrey (1) Wai, Sun (1) Mais... Palavra-chave Bactericidal/permeability-increasing protein (2) Defensin (2) Innate immunity (2) Vibrio (2) Bivalve mollusk (1) Cathelicidin (1) Lipopolysaccharide (1) Membrane transporter (1) Outer membrane vesicle (1) Pacific oyster (1) Proline-rich peptide (1) Mais... Tipo do documento Text (2) Ano 2014 (1) 2012 (1) País France (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Expression, tissue localization and synergy of antimicrobial peptides and proteins in the immune response of the oyster Crassostrea gigas ArchiMer Schmitt, Paulina; De Lorgeril, Julien; Gueguen, Yannick; Destoumieux-garzon, Delphine; Bachere, Evelyne. Diverse families of antimicrobial peptides and proteins have been described in oysters. We investigated here how antimicrobials are involved in the immune response against a pathogenic strain of Vibrio splendidus. Oyster antimicrobials were shown to display a wide variety of expression profiles in hemocyte populations and tissues. Oyster defensins are constitutively expressed in specific tissues such as mantle (Cg-Defm) or hemocytes (Cg-Defhs), while Cg-BPI is inducible and Cg-Prp appears down-regulated in hemocytes upon infection. The migratory behavior of hemocytes that express the different antimicrobials was found to be involved in the oyster response to a pathogenic Vibrio infection. Indeed, it contributes to colocalize several antimicrobials that... Tipo: Text Palavras-chave: Pacific oyster; Bivalve mollusk; Innate immunity; Bactericidal/permeability-increasing protein; Proline-rich peptide; Defensin; Vibrio. Ano: 2012 URL: http://archimer.ifremer.fr/doc/00093/20382/18267.pdf Resistance to Antimicrobial Peptides in Vibrios ArchiMer Destoumieux-garzón, Delphine; Duperthuy, Marylise; Vanhove, Audrey; Schmitt, Paulina; Wai, Sun. Vibrios are associated with a broad diversity of hosts that produce antimicrobial peptides (AMPs) as part of their defense against microbial infections. In particular, vibrios colonize epithelia, which function as protective barriers and express AMPs as a first line of chemical defense against pathogens. Recent studies have shown they can also colonize phagocytes, key components of the animal immune system. Phagocytes infiltrate infected tissues and use AMPs to kill the phagocytosed microorganisms intracellularly, or deliver their antimicrobial content extracellularly to circumvent tissue infection. We review here the mechanisms by which vibrios have evolved the capacity to evade or resist the potent antimicrobial defenses of the immune cells or tissues... Tipo: Text Palavras-chave: Vibrio; Lipopolysaccharide; Outer membrane vesicle; Membrane transporter; Innate immunity; Defensin; Cathelicidin; Bactericidal/permeability-increasing protein. Ano: 2014 URL: http://archimer.ifremer.fr/doc/00276/38767/37308.pdf Registros recuperados: 2 Primeira ... 1 ... Última

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